Galapagos receives milestone payment in antibody collaboration

Mechelen, Belgium and Galashiels, Scotland; 25 July 2007 – Galapagos NV (Euronext & LSE: GLPG) announced today the achievement of the second milestone under the collaboration with Novartis in antibodies for bone-related diseases.  Today’s milestone triggers a payment of $1 million to Galapagos.  Galapagos will pay $750,000 of this amount to ProStrakan as part of their December 2006 agreement.
 
The collaboration was initially formed between Novartis and ProSkelia SASU (formerly a subsidiary of ProStrakan) in September 2006.  Under the terms of the original agreement with Novartis, total milestones could eventually exceed $100 million, with undisclosed royalties payable on commercialization.  The first milestone payment, which was related to intellectual property, was announced on 6 December 2006.  The collaboration was then transferred to Galapagos as part of its acquisition of ProSkelia from ProStrakan on 22 December 2006.  Under the terms of Galapagos’ acquisition of ProSkelia, Galapagos and ProStrakan split milestone and royalty income from agreements existing at the time of the acquisition 25% for Galapagos and 75% for ProStrakan, while Galapagos retains all R&D fees. 
 
“We are pleased with the smooth integration of ProSkelia R&D under Galapagos management,” said Onno van Stolpe, CEO of Galapagos.  “This milestone demonstrates the progress our research team has made since the acquisition in December.”
 
Dr Wilson Totten, Chief Executive of ProStrakan added, “The terms and conditions of the sale of ProSkelia enabled us to retain an interest in future up-side from existing agreements.  We are now beginning to see the cashflow from those programmes come through and we expect this revenue stream to continue to develop and add value over the coming years.”
 
About Galapagos
Galapagos (Euronext Brussels, GLPG; Euronext Amsterdam, GLPGA; London AiM: GLPG) is a drug discovery company with clinical and pre-clinical programs in bone and joint diseases, cachexia, and menopausal hot flashes.  Its division BioFocus DPI offers a full suite of target-to-drug discovery products and services to pharmaceutical and biotech companies, encompassing target discovery and validation, screening and drug discovery through to delivery of pre-clinical candidates.  BioFocus DPI also provides adenoviral reagents for rapid identification and validation of novel drug targets, compound libraries for drug screening as well as chemogenomics and ADMET database products to select targets and compounds.  Galapagos currently employs 460 people and operates facilities in eight countries, with global headquarters in Mechelen, Belgium.  More information about Galapagos and BioFocus DPI can be found at www.glpg.com and www.biofocusdpi.com.
 
About ProStrakan
ProStrakan Group plc is a rapidly growing specialty pharmaceutical company engaged in the development and commercialisation of prescription medicines for the treatment of unmet therapeutic needs in major markets.  ProStrakan’s head office and development facilities are situated in Galashiels in Scotland. EU-wide sales and marketing of ProStrakan’s portfolio of products are handled by commercial subsidiaries in the UK, France, Germany, Spain and other EU countries. More information about ProStrakan can be found at www.prostrakan.com.
 
CONTACT
 
Galapagos NV
Onno van de Stolpe, CEO
Tel: +31 6 2909 8028
ir@glpg.com
 
Financial Dynamics (for ProStrakan)
David Yates / Ben Brewerton
Tel: +44 20 7831 3113
 
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