Disease areas
More about our work in Immunology
We strive to accelerate innovation of transformational medicines that deliver more years of life and quality of life for patients and families living with cancer.
Redefining the Future of Cancer Treatment
We are united around our mission to redefine the future of cancer treatment. Our goal is to help people facing cancer live longer, better lives. Our hope is fueled by the dream of a future free from cancer.
Unlocking hope
Addressing the unmet medical needs of cancer patients
Today, our oncology researchers passionately strive to turn cancers into manageable chronic conditions or even curable diseases.
Tomorrow, our hope is fueled by the dream of a future free from cancer. We are determined to shift the treatment paradigm of cancer.
The urgency for effective, broadly accessible treatment options and novel therapies is paramount, as the outlook for patients is often grim, with survival measured in months rather than years. That’s what fuels our ambition to redefine the future of cancer treatment.
SPEED
Speed is critical for cancer patients who cannot afford to wait to receive treatment
URGENCY
Urgent need for effective, broadly accessible treatment options and novel therapies is paramount
Combining deep disease expertise and multiple drug modalities
Cell therapy
We have groundbreaking research capabilities and a decentralized manufacturing platform for CAR-T
Small molecules
We have a long history and deep R&D experience in small molecules
Biologicals
We are building research capabilities to discover novel biological medicines
Our focus in oncology
Our current work is focused on the following hematological cancers for patients in need of additional and improved treatment options:
Non-Hodgkin’s lymphoma (NHL)
Chronic lymphocytic leukemia (CLL), including Richter transformation (RT)
Multiple myeloma (MM)
Shifting the paradigm
CAR-T cell therapy
In 2022, we entered the field of CAR-T and antibody-therapy research and development through the acquisitions of CellPoint (in the Netherlands) and Abound Bio (in the U.S). The transactions provide us with end-to-end capabilities in CAR-T therapy development and offer the potential for a paradigm shift in the space through the implementation of a breakthrough, decentralized manufacturing model and cutting-edge fully human antibody-based capabilities to design next-generation CAR-Ts.
Did you know?
~ 70%* of eligible patients do not receive CAR-T due to:
Limited capacity
Complex logistics
Restricted access
*Evidence-Based Oncology, October 2023, Volume 29, Issue 8
Personalized, decentralized
Our innovative approach to CAR-T manufacturing near the point of care
To address these challenges, we are implementing a differentiated, decentralized, point-of-care CAR-T manufacturing platform that has the potential to deliver fresh, fit cells with a seven day vein-to-vein time, enabling greater physician control and a significantly improved patient experience.
This innovative platform consists of an end-to-end xCellit® workflow management and monitoring software system, a decentralized, functionally closed, automated cell therapy manufacturing platform (using Lonza’s Cocoon®) and a proprietary quality control testing and release strategy.
CAR-T therapy model
*GMP production at a compliant manufacturing facility located at the clinic premises or in close proximity to the clinic;
The Cocoon® Platform is a registered trademark of Lonza Group AG
How Galapagos’ decentralized, innovative point-of-care CAR-T manufacturing platform can move the needle for cancer patients
Galapagos is committed to manufacturing personalized cell therapies near the point-of-care (PoC). Our ambition is to reduce the manufacturing turnaround time significantly from months or weeks to days, ensuring that patients can receive their therapy in a timely manner. Learn how in the video.
Point-of-care manufacturing, close to patients
One of the three pillars of our point-of-care platform is a decentralized, functionally closed, automated manufacturing platform for cell therapies (using Lonza’s Cocoon® Platform). Discover more about it!
Factsheet
Our commitment in oncology
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Pioneer with us in Oncology
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Do you want to pioneer for patients in Oncology? Discover our vacancies!
Partnerships
Work with us!
We combine internal and external innovation to add new capabilities, technologies and product candidates. Let’s start #PioneeringForPatients, together!
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