Director Shareholding

Galapagos NV (“the Company”)
27 June 2007
Pursuant to Rule 17 of the AiM rules for companies, Galapagos discloses that on 1 June 2007 Dirk Pollet, an Executive Committee Member of the Company, exercised 50,000 warrants at €4.00 per warrant, increasing his interest in the share capital of the Company from no shares (representing 0.00% of the share capital) to 50,000 shares (representing 0.24% of the share capital).
The Company was advised on 19 June 2007 that Dirk Pollet sold 10,000 shares at €8.62 on 11 June 2007, 10,000 shares at €8.60 on 12 June 2007, and 250 shares at €8.75 on 14 June 2007 on Euronext, decreasing his interest in the share capital of the Company from 50,000 shares (representing 0.24% of the share capital) to 29,750 (representing 0.14% of the share capital).
Galapagos NV                                                               
David Smith
Tel: +44
This release may contain forward-looking statements, including, without limitation, statements containing the words “believes,” “anticipates,” “expects,” “intends,” “plans,” “seeks,” “estimates,” “may,” “will,” “could,” “stands to,” and “continues,” as well as similar expressions.  Such forward-looking statements may involve known and unknown risks, uncertainties and other factors which might cause the actual results, financial condition, performance or achievements of Galapagos, or industry results, to be materially different from any historic or future results, financial conditions, performance or achievements expressed or implied by such forward-looking statements.  Given these uncertainties, the reader is advised not to place any undue reliance on such forward-looking statements.  These forward-looking statements speak only as of the date of publication of this document.  Galapagos expressly disclaims any obligation to update any such forward-looking statements in this document to reflect any change in its expectations with regard thereto or any change in events, conditions or circumstances on which any such statement is based, unless required by law or regulation.