Dermatomyositis (DM)

DM is a rare autoimmune disease that affects both the skin and muscles

Dermatomyositis (DM) is a rare autoimmune disease that affects both the skin and muscles. It’s estimated that the prevalence of DM is between 1 to 10 cases per million people worldwide.[22] DM primarily affects adults, with a peak age of onset between 50 and 60 years old and is more common in women than men.22

The symptoms of DM can vary from person to person, but typically involve muscle weakness and skin changes. Muscle weakness usually affects the muscles closest to the trunk of the body, such as the neck, shoulders, hips, and back. This can result in difficulty with movements like climbing stairs, getting up from a chair, or lifting objects above the head.22

Skin changes in DM can include a reddish or purple rash on the eyelids, knuckles, elbows, knees, and/or chest, and sometimes a scaly rash on the scalp or face. Over time, affected skin can become thickened and raised.22

There is currently no cure for DM, but treatment can help manage symptoms and prevent further muscle and skin damage. Treatment typically involves a combination of medications such as corticosteroids, immunosuppressants, and/or biologic agents.[23] Physical therapy and exercise may also be recommended to help improve muscle strength and function.23

At Galapagos, we are dedicated to advancing the understanding and treatment of Dermatomyositis, a rare and debilitating autoimmune disease that affects the muscles and skin.

[22] National Institute of Neurological Disorders and Stroke. (2021). Dermatomyositis Information Page. Retrieved from https://www.ninds.nih.gov/Disorders/All-Disorders/Dermatomyositis-Information-Page

[23] American College of Rheumatology. (2022). Dermatomyositis. Retrieved from https://www.rheumatology.org/I-Am-A/Patient-Caregiver/Diseases-Conditions/Dermatomyositis

Factsheet

Our commitment in immunology

Do you need everything in one place about our efforts in brightening the future of immunology?

Disease areas

More about our work in Oncology

We are united around our mission to redefine the future of cancer treatment. Our goal is to help people facing cancer live longer, better lives.

Partnerships

Work with us!

We combine internal and external innovation to add new capabilities, technologies and product candidates. Let’s start #PioneeringForPatients, together!

Galapagos Health

Explore our HCP Portal

Are you a healthcare professional? Are you looking for Galapagos’ medical education, product information or congress presence? Look no further!