Current openings

Current Openings

MECHELEN - BELGIUM

Cystic Fibrosis cell biology expert, MEC-111

Job description

You will be a member of a multidisciplinary Cystic Fibrosis (CF) team, providing strategic and scientific input on questions around protein folding, trafficking and function of the CFTR protein. You will provide expert input on the mode-of-action of small molecules modulating CFTR biology and translate this into practical experiments. You will coordinate and follow up on internal and outsourced data generation in your expertise area and critically review and interpret data on a regular basis and discuss next steps with CF team members. You will be up to date with state of the art and novel technologies in protein folding and trafficking area, implementing novel methods when appropriate.

Administrative Assistant, Mec-110

Job description

You will be responsible for supporting the Chief Scientific Officer and the Legal and Finance department. In particular, you will:

Process information stream and manage agendas
Assist in the preparation and processing of corporate documents and presentations
Perform various administrative tasks such as typing, scanning, filing, …
Interact with assistants from the local and distant sites
Perform back-up tasks in the absence of local assistant colleagues

Development Project Manager, Mec-109

Job description

You will be responsible for the organization, follow-up and integration of 1 or more drug development projects. In particular, you will:

Manage the critical time path and budget
Allocate resources externally and internally
Work with as well as challenge the team members
Generate internal and external opportunities
Remove financial, emotional or technical barriers that inhibit the progression of your projects

Development Project Leader, Mec-108

Job description

You will be responsible for the project strategy and execution of one or more development projects. In particular, you will:

Lead a cross functional team
Together with the cross functional team, generate, update and execute a development plan
Drive the project forward and towards predefined success criteria within a given budget
Communicate to senior management, alliance partners and potential licensee parties
Discuss with Key Opinion Leaders

Regulatory Affairs Expert, Mec-107

Job description

You will be responsible for the regulatory aspects of various activities that contribute to the evaluation of new drug candidates. In particular, you will:

Coordinate all regulatory activities, both in pre-clinical and clinical stages of product development, among others clinical trial applications, health authority briefing- and response documents, investigational plans for paediatrics and orphan drugs, label development
As a member of the project team, contribute to development strategy by providing regulatory advice
Actively consider scenario’s for achieving regulatory objectives with associated risks and mitigation strategies
Maintain awareness of changing regulations and guidance and share potential impact these activities may have on the product development program
Collaborate effectively with in- and external regulatory support functions

Quality and Compliance Expert, Mec-106

Job description

You will be responsible for managing the quality and compliance system that is applicable to all departments within the drug development organisation (including clinical, pre-clinical and CM&C). In particular, you will:

Assure compliance of development activities both internally and outsourced to applicable guidelines, identify potential gaps and define preventive action plans
Ensure creation and maintenance of elements (SOPs, Work Instructions, ICH-GxP, laws and policies) of the internal QMS (quality and compliance management system)
Ensuring proper training and adherence to the internal QMS and maintain initial and continuous training documentation
Perform quality audits at vendors and proactively manage corrective action plans
Prepare, conduct and report on internal quality checks (including audit of systems) and provide feedback to the departments and senior management
Act as single point of contact and coordinate inspections

Rheumatologist, Mec-105

Job description

You will be responsible for the medical aspects of clinical studies for evaluation of new drug candidates. In particular, you will:

Provide medical input from design through-out reporting for several global Phase 2 RA studies
  o Act as Medical representative in development project teams and clinical project sub-teams
  o Assist with Competent Authority and Ethics Committee/IRB submissions
  o Be the primary contact for medical review of safety information from clinical trials
  o Collaborate with the responsible for safety reporting
Collaborate with Clinical Project Managers ensuring
  o Medical aspects of protocol are carried out
  o Assessment of trial feasibility and investigator/site selection
  o Interaction with medical counterparts at CRO
Interaction with key opinion leaders
Spokesperson on medical topics to external and internal bodies
Compliance with GCP and other regulations

Clinical Project Manager, Mec-104

Job description

You will be responsible for the clinical operations activities that contribute to the early clinical evaluation of new drug candidates. In particular, you will:

Select CROs and external vendors for the conduct of planned assigned clinical studies
Discuss and manage study plans, timelines & budget with selected CRO and external vendors, from initial planning until final reporting phase
Ensure close interaction with functional experts involved in the clinical study by acting as single point of contact for assigned clinical studies
Act as clinical study representative in clinical project sub teams and/or development project teams

Manager CMC Drug Product Development, Mec-102

Job description

You will be responsible for the drug product development strategy, execution and support of filing activities (IMPD) of various development programs including:

Organization of drug product formulation development
Production of clinical supplies
Evaluation of stability data and address formulation strategy as needed
Issuance of formulation and clinical production source documents for IMPD filing
Managing the CRO’s for formulation development and clinical production
Assuring that CROs are performing according to cGMPs

Manager CMC Development – Analytical, Mec-101

Job description

You will be responsible for the CM&C analytical development strategy, execution and support of filing activities (IMPD) of various development programs including:

Organization of analytical method development, stability and analytical testing of API and drug product formulations
Evaluation of solid state characteristics of API and solid drug product formulations
Evaluation of stability data, identification and characterization of impurities and degradants
Issuance of analytical source documents for IMPD filing through consolidation of development information and reports
Managing the CRO’s for analytical development and stability testing
Organization of QC activities and quality related activities to assure that CROs are performing according to cGMPs

Manager CMC Development - Chemistry, Mec-100

Job description

You will be responsible for the drug substance development, up-scaling strategy and execution of various development programs through :

synthesis route development based on interaction with medicinal chemistry
interaction /collaboration/coordination of contractors • interaction /collaboration with development team with regards to anticipated needs
evaluation of physico-chemical data of lab scale/pilot scale batches and adjustment of processes and methods based on experience
evaluation of stability data and impurity identification/synthesis
preparation of source documents for IMPD filing
Organization of QC activities and quality related activities to assure that CROs are performing according to cGMPs

Information Scientist (m/f full time), Mec-096

Job description

The Discovery Informatics team at Galapagos has developed a Laboratory Information Management System (LIMS) to support scientific data management and decision taking within the company. In order to cope with the ever changing business, Galapagos is searching for an Information Scientist to strengthen the Discovery Informatics team.

You will be responsible for an efficient use of this LIMS by the end users, by providing help desk support, training and writing user documentation, as well as by supporting the science teams with, for example, querying databases and providing reports. You also play a key role in improving functionalities of (existing) software/systems

Due to the position in between the lab and informatics, excellent communication skills (both oral and written) are required. Being accurate and conscientious are mandatory in performing the job.

Group Leader Discovery Informatics (m/f full time), Mec-095

Job description

You will lead the discovery informatics group at our Mechelen site and coordinate activities across the other research sites as well as external consulting. You will closely collaborate with the multidisciplinary disease biology and drug discovery teams. You will be actively involved in the development, maintenance and usage of software tools and databases for target validation. You will play a key role in supporting the drug discovery teams to keep an up-to-date view on the biomedical, business and general drug discovery knowledge related to the active projects and programs. You will lay out a global strategy for LIMS developments, database maintenance and end user support in LIMS data management as well as Bioinformatics. You will efficiently manage the available resources and software budget This position offers an exciting opportunity to develop and provide information-based services to the science and business at Galapagos.

ROMAINVILLE - FRANCE

Toxicologist, RMV-050

Job description

You will support the Development team in contributing to the toxicological evaluation of new drug candidates.

In vivo ADME Scientist, RMV-049

Job description

Within Galapagos Development Department you will be in charge of the ADME characterization of the compounds issued from Galapagos Discovery projects.

LEIDEN - THE NETHERLANDS

No openings

ZAGREB - CROATIA

No openings

HARLOW - UNITED KINGDOM

No openings

SAFFRON WALDEN - UNITED KINGDOM

ADME/PK Bioanalyst, CRP-681

Job description

This is an exciting opportunity for a bioanalytical scientist with a strong understanding of LC-MS/MS and UPLC who is capable of independent troubleshooting of analytical issues.
In this lab based role your main responsibility will be to provide support to multidisciplinary projects in the CNS area. You will need excellent communication, organization and time management skills, and an ability to work independently within a multidisciplinary team.

ADME Protein LC-MS Senior Scientist, CRP-677

Job description

Your main responsibility will be to strengthen and drive our capability to assess, quantify and characterise proteins & peptides by LC-MS. You will be responsible for hands-on MS data generation, processing, interpretation and communication to project teams. The role will involve quantification of endogenous and biopharmaceutical proteins and peptides in biofluids and the study of protein-ligand interactions by mass spectrometry in the support of research projects. Located within our ADME/PK department you will also work closely with scientists in our Structural Biology, Biology and Medicinal Chemistry Divisions.

Data Scientist, CRP-652

Job description
You will contribute towards the data analysis processes from the departmental screening activities. This involves creation of analysis templates through to post screen data analysis and formatting of data files. You will have strong Microsoft Excel skills and a Life Science background. Experience with IDBS Activitybase and Genedata Screener software suites is required and familiarity with VBA, SQL, Python or Perl programming languages would be an advantage.

Compound Management Technician, CRP-651

Job description
Working alongside the compound management supervisor you will be responsible for the operation of the compound management laboratory including compound provision for HTS, interfacing with software tools, programming and running of automated pipetting sytems, as well as ensuring appropriate quality control processes are in adhered to. You will have hands-on, industrial experience in automated compound handling.

Compound Management Supervisor, CRP-650

Job description
You will manage the internal storage, handling and supply of the BioFocus screening collection of approximately 1 million compounds. You will ensure the operation is run efficiently and in line with required quality control processes and troubleshoot compound management equipment and software to maintain reliability and precision. You will have a degree in a relevant discipline with appropriate hands-on, industrial experience in compound management. Computational chemistry expertise would be advantageous.

Temporary Assay Scientist (3 months), CRP-646

Job description
We have a temporary vacancy for an enthusiastic and flexible laboratory scientist to join our Biology department where you will be expected to undertake a wide range of laboratory duties associated with the discovery of new drugs for client driven projects. You will spend a large proportion of your working day actively involved in laboratory work as part of an enthusiastic and energetic team of scientists.

Temporary in vitro ADME Senior Scientist – Maternity Contract,CRP-636

Job description
We are looking for a highly skilled ADME experimental scientist to support both multidisciplinary and stand alone DMPK programs in a drug discovery / pre-clinical setting. This is a temporary position for up to 9 months to cover for an employee on Maternity Leave. Based at our head office near Cambridge, you will support a diversity of global organizations in most therapeutic areas. As you will be handling multiple projects in parallel, you will need excellent communication, organization and time management skills, and an ability to work independently within a multidisciplinary team.

Principal Scientist – ADME/PK, CRP-606

Job description
As part of our continued success we are looking for a Principal Scientist to support both multidisciplinary and stand alone ADME/PK programs. In this client facing role your main responsibility will be to provide PK/PD support to multidisciplinary Drug Discovery projects primarily in the CNS area. You will also be required to perform and interpret in vitro ADME assays and mentor others in the application of such studies to Drug Discovery programs. As you will be handling multiple projects in parallel, you will need excellent communication, organization and time-management skills, and an ability to work independently within a multidisciplinary team.

BASEL - SWITZERLAND

No openings

Contact:

At Galapagos we aim to hire highly motivated, experienced people with integrity and excellent interpersonal and organisation skills. Since our culture is one of expected achievement through enjoyment of what we do, we are looking for individuals who thrive by working in a team-oriented environment.
In addition to the vacancies listed on the Job Openings page, we encourage speculative applications from highly skilled and enthusiastic people. If you are willing to face the challenge of joining a highly motivated entrepreneurial team, please send your CV and covering letter to the appropriate email address.

© Copyright 2012 Galapagos NV | Disclaimer